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(netarsudil ophthalmic solution) 0.02%

Inside the various layers of an eye
Inside the various layers of an eye

Mechanism of Action


See how netarsudil works to lower IOP

Rhopressa eye drops being placed into an eye.
Rhopressa eye drops being placed into an eye.

Safety & Dosing Considerations


Educate your patients about what to expect with RHOPRESSA®

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IOP=Intraocular pressure;

MOA=Mechanism of action. 


Warnings and Precautions

Bacterial Keratitis: There have been reports of bacterial keratitis associated with the use of multiple-dose containers of topical ophthalmic products. These containers had been inadvertently contaminated by patients who, in most cases, had a concurrent corneal disease or a disruption of the ocular epithelial surface.


Rhopressa® (netarsudil ophthalmic solution) 0.02% is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.



Contact Lenses: Contact lenses should be removed prior to instillation of Rhopressa® and may be inserted 15 minutes following its administration.


Adverse Reactions


The most common ocular adverse reaction observed in controlled clinical studies with Rhopressa® dosed once daily was conjunctival hyperemia, reported in 53% of patients. Six percent of patients discontinued therapy due to conjunctival hyperemia. Other common (approximately 20%) adverse reactions were: corneal verticillata, instillation site pain, and conjunctival hemorrhage. Instillation site erythema, corneal staining, blurred vision, increased lacrimation, erythema of eyelid, and reduced visual acuity were reported in 5-10% of patients.


The corneal verticillata seen in Rhopressa®- treated patients were first noted at 4 weeks of daily dosing. This reaction did not result in any apparent visual functional changes. Most corneal verticillata resolved upon discontinuation of treatment.


Please click here for full prescribing information for Rhopressa®.


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.




The recommended dosage is one drop in the affected eye(s) once daily in the evening.